NLP Analysis of Email Interactions to find automation opportunities

Finding automatization opportunities for email interactions can have positive effects for several industries, especially in tasks such as reading, receiving, writing and responding emails, categorizing emails or even to prevent loss of productivity and financial loses by dealing with spam, or improve users' satisfaction; even improving automatic categorization systems can mitigate negative impacts on personal and organization performance. Furthermore, people who work in companies spend around 28 % of their time reading and answering emails. In this project we proposed a methodology based on NLP and Unsupervised Machine Learning to look for opportunities of automation arising from recurrent email patterns found in email texts. We intent to facilitate the linguistic analysis in order to retrieve interaction patterns that can trigger automation actions. We proposed CRISP-DM methodology that lays the groundwork for detection of automatization opportunities in tasks relates. We compared the unsupervised machine learning methods K-Means, DBSCAN, and HDBSCAN with four clustering metrics applied to the Enron e-mails dataset transformed into paragraph vectors and performed several experiments with Word Mover's Distance, Euclidean Distance, L2-Norm and Cosine Similarity. Although our process yielded limited results in the detection of email interactions, we found that DBSCAN combined with Euclidean Distance was the best method among all scores. This project also contributes to the parameterization literature of said clustering algorithms as well as showing which methods, distances and scores settings are relevant for unsupervised email mining

Repetitive corrugation and straightening effect on the microstructure, crystallographic texture and electrochemical behavior for the Al-7075 alloy

Anti-corrosion susceptibility is one of the top criteria for selecting metallic materials for several industrial applications. This work studies the corrosion performance on an Al-7075 alloy obtained by Repetitive Corrugation and Straightening (RCS). This processing method generated a microstructure formed by randomly distributed micro-, submicro-, and nano- metric grain sizes. The samples exhibited a drop in corrosion resistance for a longer duration in the electrolyte and higher deformation. However, the samples processed by RCS showed better electrochemical stability in comparison with the non-deformed condition. The improvement of electrochemical stability could be associated with the particular microstructure generated during the RCS process.Postprint (published version

Intracoronary ultrasound assessment of directional coronary atherectomy: Immediate and follow-up findings

AbstractObjectives. This study was conducted to assess the relations among intracoronary ultrasound, angiographic and histologic data obtained from patients with coronary artery disease successfully treated by directional coronary atherectomy. In addition, it was designed to elucidate whether some aspects of intravascular ultrasound or pathologic findings could predict a propensity to restenosis.Background. Intracoronary ultrasound is a useful technique in guiding and assessing atherectomy. However, there is little information about the characterization of the different types of coronary plaques and the changes observed in them after resection. Furthermore, the follow-up ultrasound appearance of previously treated lesions remains undepicted.Methods. Fifty-two patients (54 ± 10 years old) were studied. All were successfully treated by atherectomy with the aid of intracoronary ultrasound guidance. Qualitative and quantitative ultrasound and angiographic variables were derived before and after resection. Quantitative histologic morphometric information was also obtained from the specimens. In 22 patients, a follow-up echoangiographic reevaluation was performed 6 ± 4 months later.Results. Echogenic plaques had a higher collagen and calcium content, whereas echolucent plaques had an increased level of fibrin, nuclel and lipids. Ultrasound plaque reduction after atherectomy was greater in echolucent (76 ± 21%) than in echogenic plaques (60 ± 18%; p < 0.05). That reduction correlated with the weight of the resected material (r = 0.62; p < 0.01). At follow-up study, 13 of 22 patients had angiographic and ultrasound evidence of restenosis. Most recurrent lesions had a stenotic three-layer appearance. The incidence of restenosis of primary lesions treated with atherectomy was higher in echolucent (100%) than in echogenic (33%) plaques. Similarly, a higher proportion of nuclear content in the resected material was observed in patients who developed restenosis (2.1 ± 0.7%) than in patients who had late success after atherectomy (1.2 ± 0.6%).Conclusions. Our findings suggest that echolucent plaques are easier to resect than are echogenic plaques but frequently develop restenosis. In contrast, the resection of echogenic plaques, although often incomplete, is associated with better long-term results

Validation and functional characterization of GWAS-identified variants for chronic lymphocytic leukemia: a CRuCIAL study

This work was partially supported by the European Union's Horizon 2020 research and innovation program (grant No 856620); grants from the Instituto de Salud Carlos III (Madrid, Spain; PI17/02256 and PI20/01845); Consejeria de Economia, Conocimiento, Empresas y Universidad (Granada, Spain; A-CTS-448-UGR18); Consejeria de Transformacion Economica, Industria, Conocimiento y Universidades (Sevilla, Spain; PY20/01282); Generalitat de Catalunya (17SGR437); Gilead Sciences Fellowship (GLD17/00282); the "Xarxa de Bancs de tumors" sponsored by Pla Director d'Oncologia de Catalunya (XBTC); the Associazione Italiana per la Ricerca sul Cancro and Fondazione Cariplo (TRIDEO 16923 and AIRC IG21436); the Spanish Association Against Cancer (AECC) Scientific Foundation grant GCTRA18022MORE; and the Consortium for Biomedical Research in Epidemiology and Public Health (CIBERESP), action Genrisk. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.In conclusion, this study confirmed the association of 31 GWASidentified SNPs with CLL risk and shed some light on the function of some of these biomarkers in the modulation of TReg, B, and T cell differentiation and proliferation, blood concentrations of B cell-related proteins, cell survival, and the expression of immuneand non-immune-related loci. Though outside the scope of the current study, it is important to mention that additional functional studies using blood samples from CLL patients are still required to validate our findings and to decipher the exact biological mechanisms behind the observed associations. A potential limitation of this work was the relatively small population size of the CRuCIAL cohort that hampered the validation of the SNPs showing modest associations.European Union's Horizon 2020 research and innovation program 856620Instituto de Salud Carlos III PI17/02256 PI20/01845Consejeria de Economia, Conocimiento, Empresas y Universidad (Granada, Spain) A-CTS-448-UGR18 Consejeria de Transformacion Economica, Industria, Conocimiento y Universidades (Sevilla, Spain) PY20/01282Generalitat de CatalunyaGeneral Electric 17SGR437Gilead Sciences GLD17/00282"Xarxa de Bancs de tumors" - Pla Director d'Oncologia de Catalunya (XBTC)Fondazione AIRC per la ricerca sul cancro Fondazione Cariplo TRIDEO 16923 AIRC IG21436Spanish Association Against Cancer (AECC) Scientific Foundation grant GCTRA18022MOREConsortium for Biomedical Research in Epidemiology and Public Health (CIBERESP), action Genris

Reflexiones sobre el sentido del diseño sistémico-interpretativo de materiales educativos

This paper summarizes a work of interpretation of the design of educational materials in the light of two interpretive contexts (which are contrasting systemic models): a enlightened modern context and a postmodern context. The discussion on the meaning of systemic-interpretive design of educational materials is by contrasting and comprehension of two different interpretations of the design of educational materials, derived from each context. The sense outlined concerns the cultivation of a holistic conception of individual and collective everyday life, based on the educational project of Interpretive Systemology.Este artículo de reflexión resume un trabajo de interpretación del diseño de materiales educativos a la luz de dos contextos interpretativos (que son modelos sistémicos contrastantes): un contexto moderno ilustrado y un contexto postmoderno. La discusión sobre el sentido del diseño sistémico-interpretativo de materiales educativos se realiza mediante el contraste y comprehensión de dos interpretaciones diferentes del diseño de materiales educativos, derivadas de cada contexto mencionado. El sentido esbozado se refiere al cultivo de una concepción holista de la cotidianidad individual y colectiva, fundamentada en el Proyecto de Educación de la disciplina de la Sistemología Interpretativa

Characteristics and Outcome of Acute Heart Failure in Infective Endocarditis: Focus on Cardiogenic Shock

Spanish Collaboration on Endocarditis—Grupo de Apoyo al Manejo de la Endocarditis Infecciosa en España (GAMES).[Background] Studies investigating the impact of cardiogenic shock (CS) on endocarditis are lacking.[Methods] Prospectively collected cohort from 35 Spanish centers (2008-2018). Logistic regression analyses were performed to identify risk factors for developing CS and predictors of mortality.[Results] Among 4856 endocarditis patients, 1652 (34%) had acute heart failure (AHF) and 244 (5%) CS. Compared with patients without AHF and AHF but no CS, patients with CS presented higher rates of surgery (40.5%, 52.5%, and 68%; P < .001) and in-hospital mortality (16.3%, 39.1%, and 52.5%). Compared with patients with septic shock, CS patients presented higher rates of surgery (42.5% vs 68%; P < .001) and lower rates of in-hospital and 1-year mortality (62.3% vs 52.5%, P = .008, and 65.3% vs 57.4%, P = .030). Severe aortic and mitral regurgitation (OR [95% CI], 2.47 [1.82-3.35] and 3.03 [2.26-4.07]; both P < .001), left-ventricle ejection fraction <60% (1.72; 1.22-2.40; P = .002), heart block (2.22; 1.41-3.47; P = .001), tachyarrhythmias (5.07; 3.13-8.19; P < .001), and acute kidney failure (2.29; 1.73-3.03; P < .001) were associated with higher likelihood of developing CS. Prosthetic endocarditis (2.03; 1.06 -3.88; P = .032), Staphylococcus aureus (3.10; 1.16 -8.30; P = .024), tachyarrhythmias (3.09; 1.50-10.13; P = .005), and not performing cardiac surgery (11.40; 4.83-26.90; P < .001) were associated with a higher risk of mortality.[Conclusions] AHF is common among patients with endocarditis. CS is associated with high mortality and should be promptly identified and assessed for cardiac surgery.This work was supported by the Ministerio de Sanidad y Consumo of Spain (grant number FIS NCT00871104; Instituto de Salud Carlos III). Institut d’Investigacions Biomèdiques Pi i Sunyer (IDIBAPS) provided J. M. M. with a persobal IDIBAPS 80:20 research grant during 2017–2021. M. H. M. held a Rio Hortega Research Grant (CM17/00062) from the Instituto de Salud Carlos III” and the Ministerio de Economia y Competitividad, Madrid (Spain) in 2018–2020.Peer reviewe

Measurement of the inclusive and dijet cross-sections of b-jets in pp collisions at sqrt(s) = 7 TeV with the ATLAS detector

The inclusive and dijet production cross-sections have been measured for jets containing b-hadrons (b-jets) in proton-proton collisions at a centre-of-mass energy of sqrt(s) = 7 TeV, using the ATLAS detector at the LHC. The measurements use data corresponding to an integrated luminosity of 34 pb(-1). The b-jets are identified using either a lifetime-based method, where secondary decay vertices of b-hadrons in jets are reconstructed using information from the tracking detectors, or a muon-based method where the presence of a muon is used to identify semileptonic decays of b-hadrons inside jets. The inclusive b-jet cross-section is measured as a function of transverse momentum in the range 20 -dijet cross-section is measured as a function of the dijet invariant mass in the range 110 < m(jj) < 760 GeV, the azimuthal angle difference between the two jets and the angular variable chi in two dijet mass regions. The results are compared with next-to-leading-order QCD predictions. Good agreement is observed between the measured cross-sections and the predictions obtained using POWHEG + Pythia. MC@NLO + Herwig shows good agreement with the measured b (b) over bar -dijet cross-section. However, it does not reproduce the measured inclusive cross-section well, particularly for central b-jets with large transverse momenta

Properties of jets measured from tracks in proton-proton collisions at center-of-mass energy sqrt(s) = 7 TeV with the ATLAS detector

Jets are identified and their properties studied in center-of-mass energy sqrt(s) = 7 TeV proton-proton collisions at the Large Hadron Collider using charged particles measured by the ATLAS inner detector. Events are selected using a minimum bias trigger, allowing jets at very low transverse momentum to be observed and their characteristics in the transition to high-momentum fully perturbative jets to be studied. Jets are reconstructed using the anti-k(t) algorithm applied to charged particles with two radius parameter choices, 0.4 and 0.6. An inclusive charged jet transverse momentum cross section measurement from 4 GeV to 100 GeV is shown for four ranges in rapidity extending to 1.9 and corrected to charged particle-level truth jets. The transverse momenta and longitudinal momentum fractions of charged particles within jets are measured, along with the charged particle multiplicity and the particle density as a function of radial distance from the jet axis. Comparison of the data with the theoretical models implemented in existing tunings of Monte Carlo event generators indicates reasonable overall agreement between data and Monte Carlo. These comparisons are sensitive to Monte Carlo parton showering, hadronization, and soft physics models

Measurement of the top quark pair production cross section in pp collisions at sqrt(s) = 7 TeV in dilepton final states with ATLAS

A measurement of the production cross section of top quark pairs (t (t) over bar) in proton-proton collisions at a center-of-mass energy of 7 TeV recorded with the ATLAS detector at the Large Hadron Collider is reported. Candidate events are selected in the dilepton topology with large missing transverse energy and at least two jets. Using a data sample corresponding to an integrated luminosity of 35 pb(-1), a t (t) over bar production cross section sigma(t (t) over bar) = 177 +/- 20(stat.) +/- 14(syst.) +/- 7(lum.) pb is measured for an assumed top quark mass of m(t) = 172.5 GeV. A second measurement requiring at least one jet identified as coming from a b quark yields a comparable result, demonstrating that the dilepton final states are consistent with being accompanied by b-quark jets. These measurements are in good agreement with Standard Model predictions